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Teepu Siddique, MD

Northwestern Medical Group
  • Neurology

BIOGRAPHY




Neurologist Teepu Siddique MD, the Les Turner ALS Foundation/Herbert C. Wenske Foundation Professor at the Northwestern University Feinberg School of Medicine, is a clinician-scientist who has directed the Division of Neuromuscular Medicine and the Les Turner ALS Foundation Laboratory at Northwestern since 1991. Dr. Siddique’s research has focused on the molecular genetics of several neuromuscular diseases, particularly amyotrophic lateral sclerosis (ALS, commonly called Lou Gehrig disease) and ALS with dementia.  He has employed a range of strategies to identify several genes that cause inherited ALS, particularly SOD1, ALSIN, FUS, UBQLN2 and SQSTM1, as well as additional genetic loci. His research team developed the first animal model of for any neurodegenerative disease, the SOD1 transgenic mouse in 1994.  Since then they have developed several other models, using them to study disease mechanism and test potential therapies. His recent work with UBQLN2 and SQSTMI demonstrated that a defect in protein degradation pathways is a common disease mechanism in all types of ALS, sporadic as well as inherited, and the ALS-dementias.  This has paved the way for targeted, and therefore effective, treatments of ALS.  A recent editorial in the journal Neurology, the most widely read and quoted journal in the field, cited both Dr. Siddique’s identification of the first causative gene in ALS in 1993 and his team’s 2010 report of malfunction in the ubiquitin-proteasome system as paradigm shifts in understanding ALS.



 



Professor Siddique has received numerous national and international awards, including the first Shelia Essey Award in ALS from the American Academy of Neurology, the Hope through Caring Award from the Les Turner ALS Foundation and the Forbes Norris Award from the International Alliance of ALS-MND Associations.



 

EDUCATION


  • Medical Education
    Dow Medical College (Pakistan) - 1973
  • Residency
    Umdnj-University Hospital - 1979
  • Fellowship
    National Institutes of Health - 1981

BOARD CERTIFICATION


  • Neurology

PRIMARY LOCATION


Northwestern Medical Group

675 N. St. Clair

Galter 20-100

Chicago, IL 60611

312-695-7950
Wednesday
8:30 a.m. - 12:30 p.m.
Thursday
1:00 p.m. - 6:00 p.m.

CLINICAL INTERESTS


  • ALS
  • Dysimmune Neuropathy
  • Heredity Spastic Parapareses
  • Motorneuron Disease
  • Muscular Dystrophy
  • Myasthenia Gravis
  • Neurogenetic Disorders
  • Neuromuscular Disease
  • Primary Lateral Sclerosis
  • Spinocerbellar Ataxia

LANGUAGES


  • Urdu

ACCEPTED INSURANCE


  • Aetna EPO
  • Aetna HMO
  • Aetna POS
  • Aetna PPO
  • Aetna US Healthcare HMO
  • BCBS Classic Blue
  • BCBS PPO
  • Beech Street
  • Blue Choice Supervalu PPO
  • Cigna EPO
  • Cigna HMO
  • Cigna POS
  • Cigna PPO
  • Coventry Health Plan PPO
  • HFN-Healthcares Finest Network
  • Humana ChoiceCare POS
  • Humana ChoiceCare PPO
  • Humana HMO
  • Medicaid
  • Medicare
  • Multiplan PPO
  • PHCS EPO
  • PHCS POS
  • PHCS PPO
  • PNA (Preferred Network Access)
  • PPO Next
  • Preferred Plan PPO
  • TriCare(US Military Insurance)
  • Unicare PPO
  • Unicare PPO(Wellpoint Network)
  • UnitedHealthcare Choice
  • UnitedHealthcare Choice Plus
  • UnitedHealthcare Options PPO
  • UnitedHealthcare Select
  • UnitedHealthcare Select HMO
  • UnitedHealthcare Select Plus